How a Veridryx research lot is made and released
Our peptides are produced by solid-phase synthesis at qualified manufacturing partners, purified by preparative HPLC, freeze-dried and tested before a lot is released.
Process control is what makes results comparable
Two lots of the same compound should behave the same in your assay. That depends on a consistent process and on testing that catches a lot that drifted.
Identity
Mass spectrometry confirms each lot is the intended molecule.
Contaminant screening
Endotoxin and residual solvents are tested where listed for the lot.
Independent records
Results are documented per lot and matched to the label.
From amino acids to a sealed vial
Synthesis
The peptide chain is built one amino acid at a time on a solid resin support (solid-phase peptide synthesis).
- Protected amino acids coupled in sequence
- Cleavage from the resin
- Crude product characterized
Purification
Preparative HPLC separates the target peptide from truncated and side-reaction products.
- Fractions collected and analyzed
- Only on-target fractions pooled
- Salt form recorded
Fill and release
The purified peptide is filled into vials and freeze-dried, then tested before release.
- Lyophilization for stability
- Lot number on every label
- Released only with a complete COA
The full process
- 1
Sequence and specification
The target sequence, salt form and acceptance criteria are set for the product.
- 2
Solid-phase synthesis
Amino acids are coupled in order on a resin support.
- 3
Cleavage
The finished chain is cleaved from the resin and protecting groups are removed.
- 4
Crude analysis
The crude peptide is checked by analytical HPLC and mass spectrometry.
- 5
Preparative purification
Preparative HPLC isolates the target peptide.
- 6
Pooling
Fractions that meet specification are combined into a single lot.
- 7
Lyophilization
The lot is filled into vials and freeze-dried into a stable powder.
- 8
Lot testing
Purity and identity are tested, with endotoxin and residual solvents where listed.
- 9
Review and release
Results are reviewed against the specification; only passing lots are released.
- 10
Labeling and storage
Vials are labeled with the lot number and stored cold until shipment.
What is documented for each lot
HPLC purity
Main-peak area percentage with chromatogram and method conditions.
Mass spectrometry
Observed molecular mass compared with the expected mass.
Endotoxin
LAL result in EU/mg, where the lot has been tested.
Residual solvents
Headspace GC results, where the lot has been tested.
Appearance
Description of the lyophilized cake and vial condition.
Lot record
Lot number, test dates and the laboratory that ran each test.
A certificate, line by line
This is the layout our certificates follow. Real results are on each lot's own certificate in the Testing Library.
Find the data for your lot
Search the Testing Library by lot number, or ask us for a report.
RESEARCH USE ONLY
Veridryx supplies research materials to qualified buyers for in-vitro and laboratory research only. Products are not drugs, dietary supplements, foods or cosmetics, are not intended for human or veterinary use, and have not been evaluated by the U.S. Food and Drug Administration. We do not provide dosing, administration or human-use guidance. See our Research Use Policy.